At the end of the course, the student should be able to: demonstrate his knowledge and understanding onthe:

1. Molecular and functional organization of a cell, and sub- cellular components;

2. Structure, function and interrelationship of biomolecules and consequences of deviation from normal;

3. Basic and clinical aspects of enzymology and regulation of enzymatic activity;

4. Digestion and assimilation of nutrients and consequences of malnutrition;

5. Integration of the various aspects of metabolism, and their regulatory pathways;

6. Biochemical basis of inherited disorders and their associated sequelae;

7. Mechanisms involved in maintenance of body fluid and pH homeostasis;

8. Molecular mechanisms of gene expression and regulation, the principles of genetic engineering

andtheir application in medicine;

9. Molecular concepts of body defense and their application in medicine;

10. Biochemical basis of environmental health hazards; and biochemical basis of cancer and carcinogenesis, principles of metabolism, and detoxification of Xenobiotics.

11. Principles of various conventional and specialized laboratory investigations and instrumentation, analysis and interpretation of a given data; the ability to suggest experiments to support theoretical concepts and clinical diagnosis.