性别: 女
职称:研究员 博导,硕导
学历:研究生
学位:博士
电话:020-85220261
电子邮件:lysong2004@126.com
简介:
已在高校从事教学与科研工作30余年。教学方面主要承担国际学院药学专业《生物药剂学与药物动力学》等课程的全英教学工作;科研方面主要从事肿瘤与免疫药理学研究以及中药有效成分筛选与作用机制研究。发表学术论文38篇(其中SCI期刊收录论文17篇),参编教材/学术专著8部,申请发明专利4项。主持或参加国家级与省部级科研课题10余项。
主要研究方向:
1. 肿瘤与免疫药理学
2. 中药药效及分子生物学基础
3. 创新药物的研究和开发
近年来承担的主要科研项目:
1.国家自然科学基金面上项目(81374015):海洋中药毛蚶抗肿瘤活性物质基础及其作用机制研究,资助经费70万元(课题负责人)
2.“十二五”国家科技重大专项/重大新药创制课题(2011ZX09102-001-33):抗肿瘤生物新药ACM,研究经费300万元(课题负责人)
3.“十一五”国家科技重大专项/重大新药创制课题(2009ZX09103-726):抗肿瘤海洋生物新药JNY-1,研究经费150万元(子课题负责人)
4.国家自然科学基金(81274045):基于植物干细胞培养体系的长春新碱生物合成途径及其代谢调控机理研究,研究经费70万元(第二负责人)
5.广东省科技计划重大专项课题(2004A30505003):抗癌新药注射用JNY-1冻干粉针的研制开发,研究经费40万元(药效与毒理学研究负责人)
6.广州市科技计划项目课题(2006Z3-E5031):抗癌中药新药ACM胶囊的研制开发,研究经费30万元(课题负责人)
7.广州市科技计划重点课题(2005Z2-E4031):抗癌新药注射用JNY-1冻干粉针的研制开发,研究经费50万元(药效与毒理学研究负责人)
近五年代表性论著或专利(第一作者或通讯作者):
1.Lili Chen, Liyan Song*, Tingfei Li, Jianhua Zhu, Jian Xu, Qin Zheng, Rongmin Yu. A new antiproliferative and antioxidant peptide isolated from Arca subcrenata. Mar Drugs 2013, 11:1800-1814.
2.Xianjing Hu, Liyan Song*, Lijiao Huang, Qin Zheng, Rongmin Yu. Antitumor effect of a polypeptide fraction from Arca subcrenata in vitro and in vivo. Mar Drugs 2012, 10:2782-2794.
3.Li Yang, Jianhua Zhu, Liyan Song*, Xiaojian Shi, Xingyi Li, Rongmin Yu. Three sesquiterpene compounds biosynthesized from artemisinic acid using suspension-cultured cells of Averrhoa carambola. Nat Prod Res 2012, 26:1388-1394.
4.Liangbin Zhou, Tian Tian, Bailin Xue, Liyan Song*, Ling Liu, Rongmin Yu. Biosynthesis of coumarin glycosides by transgenic hairy roots of Polygonum multiflorum. Biosci Biotechnol Biochem 2012, 76:1008-1010.
5.Xuqiao Hu, Yuanyuan Huang, Quanfeng Dong, Liyan Song*, Fei Yuan, Rongmin Yu. Structure characterization and antioxidant activity of a novel polysaccharide isolated from pulp tissues of Litchi chinensis. J Agric Food Chem 2011, 59:11548-11552.
6.Yin Yin, Rongmin Yu, Wei Yang, Fei Yuan, Chunyan Yan, Liyan Song*. Structural characterization and anti-tumor activities of a heteropolysaccharide isolated from Taxus yunnanensis. Carbohydr Polym 2010, 82:543-548.
7.Fei Yuan, Rongmin Yu, Yin Yin, Jianru Shen, Quanfeng Dong, Ling Zhong, Liyan Song*. Structure characterization and antioxidant activity of a novel polysaccharide isolated from Ginkgo biloba. Int J Biol Macromol 2010, 46:436-439.
8.Rongmin Yu, Yin Yin, Wei Yang, Weili Ma, Lin Yang, Xiujuan Chen, Zhang Zhang, Bin Ye, Liyan Song*. Structural elucidation and biological activity of a novel polysaccharide by alkaline extraction from cultured Cordyceps militaris. Carbohydr Polym 2009, 75:166-171.
9.Liyan Song, Tingfei Li, Rongmin Yu, Chunyan Yan, Shengfang Ren, Yu Zhao. Antioxidant activities of hydrolysates of Arca subcrenata prepared with three proteases. Mar Drugs 2008, 6:607-619.
10.Liyan Song, Shengfang Ren, Rongmin Yu, Chunyan Yan, Tingfei Li, Yu Zhao. Purification, characterization and in vitro anti-tumor activity of proteins from Arca subcrenata Lischke. Mar Drugs 2008, 6:418-430.
地址:广州市黄埔大道西601号 暨南大学(邮编:510632)
电话:0086-20-85226662
邮箱:ogj@jnu.edu.cn
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